Regular Article

Facile fabrication of silicon coating for improving biodegradation and cytocompatibility of pure magnesium by hydrothermal method

College of Ecological Environment and Urban Construction, Fujian University of Technology, Fuzhou 350118 PR China

^* e-mail: maliyan9722@21cn.com

Received: 20 April 2018
Accepted: 7 January 2019

Abstract

In this study, a bioactive silicon coating was fabricated for reducing the degradation rate and enhancing the cytocompatibility of the pure magnesium. The morphology and phase of coating were characterized by a scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDS), X-ray diffractometer (XRD), and X-ray photoelectron spectroscopy (XPS), respectively. The electrochemical and immersion tests were conducted in a simulated body fluid to evaluate the in vitro degradation behavior of the Si-coated sample. Cell viability and cell adhesion assays of human osteosarcoma cells were performed to determine the biocompatibility of the Si-coating. The XRD pattern suggested that MgO, Mg₂SiO₄ and SiO₂ were formed on the Si-coated sample. The results of the electrochemical and immersion tests showed that the Si-coating could significantly decrease degradation rate of the pure magnesium. Meanwhile, the Si-coating could significantly promote the cell adhesion, migration and proliferation in vitro. It is considered that the Si-coating showed a promising application in improving the anticorrosion and biocompatibility of the pure magnesium.